PDE6A Antikörper (N-Term)

Produktnummer ABIN302532

Produktdetails anti-PDE6A Antikörper

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE6A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects Phosphodiesterase 6A (PDE6A) at N-terminal region.

Aufreinigung: Immunoaffinity chromatography

Immunogen: PDE6A antibody was raised against synthetic peptide from N-terminal region of human PDE6A / PDE6 Alpha.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.23 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu PDE6A

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Andere Bezeichnung: PDE6A (PDE6A Produkte)

Synonyme: si:bz1d10.3 antikoerper, si:rp71-1d10.3 antikoerper, CGPR-A antikoerper, PDEA antikoerper, RP43 antikoerper, Pdea antikoerper, nmf282 antikoerper, phosphodiesterase 6A, cGMP-specific, rod, alpha antikoerper, phosphodiesterase 6A antikoerper, pde6a antikoerper, PDE6A antikoerper, Pde6a antikoerper

Hintergrund: Phosphodiesterase 6A, a catalytic subunit of the photoreceptor phosphodiesterase, has been shown to affect functioning of eye retina as the alpha subunit of the heterotetrameric rod photoreceptor. Mutations in PDE6A have been identified as a cause of autosomal recessive retinitis pigmentosa.Synonyms: 5'-cyclic phosphodiesterase subunit alpha, GMP-PDE alpha, PDE V-B1, PDE6 alpha, PDEA, Phosphodiesterase 6A, Phosphodiesterase-6A cGMP-specific, Rod cGMP-specific 3'

Gen-ID: 5145

NCBI Accession: NP_000431

UniProt: P16499

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction