PDE9A Antikörper
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- Target Alle PDE9A Antikörper anzeigen
- PDE9A (phosphodiesterase 9A (PDE9A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDE9A Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects Phosphodiesterase 9A (PDE9A) at internal domain.
- Aufreinigung
- Immunoaffinity chromatography
- Immunogen
- PDE9A antibody was raised against synthetic peptide from human PDE9A.
- Top Product
- Discover our top product PDE9A Primärantikörper
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- Applikationshinweise
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Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.09 % sodium azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- Target
- PDE9A (phosphodiesterase 9A (PDE9A))
- Andere Bezeichnung
- PDE9A (PDE9A Produkte)
- Synonyme
- PDE9A antikoerper, MGC116558 antikoerper, Pde9a antikoerper, HSPDE9A2 antikoerper, PDE9A1 antikoerper, phosphodiesterase 9A antikoerper, phosphodiesterase 9A S homeolog antikoerper, high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A antikoerper, PDE9A antikoerper, pde9a.S antikoerper, Pde9a antikoerper, LOC100549810 antikoerper, pde9a antikoerper
- Hintergrund
- Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.Synonyms: 5'-cyclic phosphodiesterase 9A, HSPDE9A2, High affinity cGMP-specific 3', Phosphodiesterase 9A, Phosphodiesterase PDE9A21
- Gen-ID
- 5152
- NCBI Accession
- NP_001001567
- UniProt
- O76083
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