PDE7B Antikörper (N-Term)

Produktnummer ABIN302520

Der Kaninchen Polyklonal anti-PDE7B Antikörper (ABIN302520) detektiert spezifisch PDE7B in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PDE7B Antikörper (N-Term) (ABIN302520)

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE7B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PDE7B Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects Phosphodiesterase 7B (PDE7B) near N-terminus.

Aufreinigung: Immunoaffinity chromatography

Immunogen: PDE7B antibody was raised against synthetic peptide from near N-terminus of human PDE7B.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu PDE7B

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Andere Bezeichnung: PDE7B

Hintergrund: Phosphodiesterase 7B, a cAMP-specific phosphodiesterase, has been shown to affect cAMP-mediated neural activity and cAMP metabolism in the brain. PDE7B activity is inhibited by dipyridamole, IBMX, and SCH51866. At least three splice variants have been isolated for PDE7B from rats and they show tissue specific expression patterns.Synonyms: 5'-cyclic phosphodiesterase 7B, MGC88256, Phosphodiesterase 7B, cAMP-specific 3', rolipram-insensitive phosphodiesterase type 7

Gen-ID: 27115

NCBI Accession: NP_061818

UniProt: Q9NP56

Pathways: cAMP Metabolic Process