Fibronectin Antikörper
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- Target Alle Fibronectin Antikörper anzeigen
- Fibronectin
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Reaktivität
- Human, Maus, Ratte, Schwein
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Fibronectin Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.
- Klon
- TV-1
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product Fibronectin Primärantikörper
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- Applikationshinweise
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Fibronectin antibody to be titered up or down for optimal performance.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the Fibronectin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- Fibronectin
- Abstract
- Fibronectin Produkte
- Synonyme
- FN antikoerper, cig antikoerper, fibronectin antikoerper, finc antikoerper, lets antikoerper, msf antikoerper, CIG antikoerper, ED-B antikoerper, FINC antikoerper, FNZ antikoerper, GFND antikoerper, GFND2 antikoerper, LETS antikoerper, MSF antikoerper, E330027I09 antikoerper, Fn antikoerper, Fn-1 antikoerper, FIBNEC antikoerper, fn-1 antikoerper, fibronectin 1 antikoerper, FN1 antikoerper, fn1 antikoerper, Fn1 antikoerper
- Hintergrund
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Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. There are two types of fibronectin: soluble fibronectin which is produced by hepatocytes and found in blood plasma, and insoluble cellular fibronectin which is produced by fibroblasts in a soluble form and latter assembled into an insoluble form via fibril formation.
This antibody reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this antibody localizes to tumor vessels where it binds to the underlying basement. The Fibronectin epitope recognized by this antibody is not accessible in normal tissues to the circulating antibody indicating that it can be used to specifically target tumor vessels in vivo. Clone TV-1 fibronectin antibody is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or antibodies.
- Gen-ID
- 2335
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