CD6 Antikörper

Produktnummer ABIN3024446

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD6 in FACS, WB und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CD6 Antikörper (ABIN3024446)

Target: CD6

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD6 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Klon: SPV-L14

Produktdetails anti-CD6 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD6 antibody should be determined by the researcher.\. Western blot: 1-2 μg/mL, Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CD6

Target: CD6

Andere Bezeichnung: CD6

Hintergrund: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular "scavenger receptor cysteine-rich" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.