Der Maus Monoklonal anti-CD147 Antikörper (Klon CB43) (ABIN3024283) detektiert spezifisch CD147 in FACS und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Optimal dilution of the Emmprin antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the Emmprin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Target
CD147 (BSG)
(Basigin (Ok Blood Group) (BSG))
Andere Bezeichnung
Emmprin
Hintergrund
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.