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TYR Antikörper

This anti-TYR antibody (ABIN3024010) is a Mouse Monoclonal antibody detecting TYR in WB, IF, FACS, IHC (p). Suitable for Human.
Produktnummer ABIN3024010

Kurzübersicht für TYR Antikörper (ABIN3024010)

Target

Alle TYR Antikörper anzeigen
TYR (Tyrosinase (TYR))

Reaktivität

  • 100
  • 24
  • 23
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 72
  • 37
Maus

Klonalität

  • 60
  • 50
Monoklonal

Konjugat

  • 65
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TYR Antikörper ist unkonjugiert

Applikation

  • 60
  • 40
  • 33
  • 29
  • 27
  • 20
  • 19
  • 17
  • 14
  • 13
  • 13
  • 9
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

T311
  • Aufreinigung

    Protein G affinity chromatography

    Immunogen

    Recombinant Tyrosinase protein was used as the immunogen for this antibody.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 1  mM EDTA,  pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 2-5 μg/mL, FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.2 mg/mL

    Buffer

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store the Tyrosinase antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target

    TYR (Tyrosinase (TYR))

    Andere Bezeichnung

    Tyrosinase

    Hintergrund

    Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

    Gen-ID

    7299
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