XCR1 Antikörper

Produktnummer ABIN302346

Der Kaninchen Polyklonal anti-XCR1 Antikörper (ABIN302346) detektiert spezifisch XCR1 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für XCR1 Antikörper (ABIN302346)

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XCR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-XCR1 Antikörper

Spezifität: This antibody detects Chemokine (C Motif) XC Receptor 1 (CCXCR1).

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human XCR1.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu XCR1

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Andere Bezeichnung: XCR1 / GPR5

Hintergrund: CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease.Synonyms: CCXCR1, Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1

Gen-ID: 2829

NCBI Accession: NP_001019815

UniProt: P46094