DRD3 Antikörper (Cytoplasmic Domain)

Produktnummer ABIN302336

Der Kaninchen Polyklonal anti-DRD3 Antikörper wird verwendet zum Nachweis von DRD3 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für DRD3 Antikörper (Cytoplasmic Domain) (ABIN302336)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DRD3 Antikörper

Bindungsspezifität: Cytoplasmic Domain

Spezifität: This antibody detects Dopamine Receptor D3 (DRD3).

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: DRD3 antibody was raised against synthetic peptide from 3rd cytoplasmic domain of human DRD3 / Dopamine Receptor D3.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Andere Bezeichnung: Dopamine D3 Receptor

Hintergrund: The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.Synonyms: D(3) Dopamine receptor, D3DR, DRD3, Dopamin receptor D3, ETM1, FET1

Gen-ID: 1814

NCBI Accession: NP_000787

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity