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Histone 3 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-Histone 3-Antikörper wurde für WB, IHC, ChIP und IP validiert. Er ist geeignet, Histone 3 in Proben von Human zu detektieren. Es sind 6+ Publikationen verfügbar.
Produktnummer ABIN3023243

Kurzübersicht für Histone 3 Antikörper (C-Term) (ABIN3023243)

Target

Alle Histone 3 (H3) Antikörper anzeigen
Histone 3 (H3) (Histone H3 (H3))

Reaktivität

  • 1352
  • 910
  • 812
  • 41
  • 39
  • 39
  • 34
  • 34
  • 26
  • 23
  • 21
  • 21
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 1156
  • 255
  • 12
  • 5
Kaninchen

Klonalität

  • 1074
  • 353
  • 1
Polyklonal

Konjugat

  • 816
  • 72
  • 47
  • 46
  • 44
  • 44
  • 44
  • 44
  • 29
  • 27
  • 18
  • 18
  • 18
  • 17
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  • 17
  • 17
  • 17
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  • 17
  • 17
  • 17
  • 7
  • 1
Dieser Histone 3 Antikörper ist unkonjugiert

Applikation

  • 1028
  • 418
  • 374
  • 322
  • 252
  • 202
  • 188
  • 186
  • 164
  • 163
  • 148
  • 127
  • 115
  • 58
  • 48
  • 48
  • 35
  • 22
  • 16
  • 14
  • 7
  • 7
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)
  • Bindungsspezifität

    • 56
    • 50
    • 48
    • 44
    • 43
    • 37
    • 37
    • 36
    • 35
    • 35
    • 34
    • 33
    • 32
    • 31
    • 31
    • 30
    • 23
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    • 22
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    • 19
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    • 9
    • 9
    • 9
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    • 8
    • 8
    C-Term

    Sequenz

    REIRRYQKST ELLIRKLPFQ RLMREIAQDF KTDLRFQSSA VMALQEACES YLVGLFEDTN LCVIHAKRVT IMPKDIQLAR RIRGERA

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human HIST3H3 (NP_003484.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Hou, Han, Fei, Gao, Qi, Cai, Qi: "Dietary Flavone Tectochrysin Exerts Anti-Inflammatory Action by Directly Inhibiting MEK1/2 in LPS-Primed Macrophages." in: Molecular nutrition & food research, Vol. 62, Issue 2, (2018) (PubMed).

    Tang, Guo, Zhu, Huang, Liu, Cai, Yu, Wang: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." in: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).

    Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

    Su, Li, Lei, Wang, Zhao, Cai, Wang, Li, Wu: "The EZH1-SUZ12 complex positively regulates the transcription of NF-κB target genes through interaction with UXT." in: Journal of cell science, Vol. 129, Issue 12, pp. 2343-53, (2017) (PubMed).

    Yu, Tong, Luo, Xue, Mei, Ma, Yu, Mao, Kong, Yu, Li: "Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites." in: PLoS ONE, Vol. 12, Issue 4, pp. e0175576, (2017) (PubMed).

    Ji, Liu, Zhao, Liu, Guo, Guan, Zhou, Guo: "NF-κB Signaling is Involved in the Effects of Intranasally Engrafted Human Neural Stem Cells on Neurofunctional Improvements in Neonatal Rat Hypoxic-Ischemic Encephalopathy." in: CNS neuroscience & therapeutics, Vol. 21, Issue 12, pp. 926-35, (2016) (PubMed).

  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Andere Bezeichnung

    Histone H3

    Hintergrund

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Histone H3

    Molekulargewicht

    15 kDa

    Gen-ID

    8290

    UniProt

    Q16695
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