NPPB Antikörper (AA 1-134)

Produktnummer ABIN3023136

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NPPB in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NPPB Antikörper (AA 1-134) (ABIN3023136)

Target: NPPB (Natriuretic Peptides B (NPPB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NPPB Antikörper

Bindungsspezifität: AA 1-134

Sequenz: MDPQTAPSRA LLLLLFLHLA FLGGRSHPLG SPGSASDLET SGLQEQRNHL QGKLSELQVE QTSLEPLQES PRPTGVWKSR EVATEGIRGH RKMVLYTLRA PRSPKMVQGS GCFGRKMDRI SSSSGLGCKV LRRH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human BNP (NP_002512.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NPPB

Target: NPPB (Natriuretic Peptides B (NPPB))

Andere Bezeichnung: NPPB

Hintergrund: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.,NPPB,BNP,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Cardiovascular,Angiogenesis,Blood,Blood Pressure regulation,Heart,Hypertrophy,NPPB

Molekulargewicht: 14 kDa

Gen-ID: 4879

UniProt: P16860

Pathways: Hormone Activity