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ALOX5 Antikörper (AA 1-300)

Dieses Anti-ALOX5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ALOX5 in WB, IHC und IF. Geeignet für Human.
Produktnummer ABIN3023073

Kurzübersicht für ALOX5 Antikörper (AA 1-300) (ABIN3023073)

Target

Alle ALOX5 Antikörper anzeigen
ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reaktivität

  • 108
  • 81
  • 63
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 114
  • 23
  • 1
Kaninchen

Klonalität

  • 112
  • 26
Polyklonal

Konjugat

  • 72
  • 11
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser ALOX5 Antikörper ist unkonjugiert

Applikation

  • 86
  • 47
  • 39
  • 39
  • 29
  • 25
  • 24
  • 14
  • 9
  • 7
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 17
    • 15
    • 15
    • 14
    • 13
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300

    Sequenz

    MPSYTVTVAT GSQWFAGTDD YIYLSLVGSA GCSEKHLLDK PFYNDFERGA VDSYDVTVDE ELGEIQLVRI EKRKYWLNDD WYLKYITLKT PHGDYIEFPC YRWITGDVEV VLRDGRAKLA RDDQIHILKQ HRRKELETRQ KQYRWMEWNP GFPLSIDAKC HKDLPRDIQF DSEKGVDFVL NYSKAMENLF INRFMHMFQS SWNDFADFEK IFVKISNTIS ERVMNHWQED LMFGYQFLNG CNPVLIRRCT ELPEKLPVTT EMVECSLERQ LSLEQEVQQG NIFIVDFELL DGIDANKTDP

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ALOX5 (NP_000689.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

    Andere Bezeichnung

    ALOX5

    Hintergrund

    This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ALOX5,5-LO,5-LOX,5LPG,LOG5,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,ALOX5

    Molekulargewicht

    56 kDa/61 kDa/71 kDa/74 kDa/77 kDa

    Gen-ID

    240

    UniProt

    P09917
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