PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze / thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
SPDYA
(Speedy Homolog A (SPDYA))
Andere Bezeichnung
SPDYA
Hintergrund
Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2.,SPDYA,RINGO3,RINGOA,SPDY1,SPY1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SPDYA