ATRX Antikörper

Produktnummer ABIN302283

Der Maus Monoklonal anti-ATRX Antikörper (Klon 60-1) (ABIN302283) detektiert spezifisch ATRX in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ATRX Antikörper (ABIN302283)

Target: ATRX (helicase 2, X-linked (ATRX))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATRX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 60-1

Produktdetails anti-ATRX Antikörper

Spezifität: This antibody detetcs X-Linked Helicase II (ATRX).

Produktmerkmale: Synonyms: RAD54L, XNP, Znf-HX, Transcriptional regulator ATRX, X-linked helicase II, X-linked nuclearprotein

Aufreinigung: Protein G chromatography

Immunogen: Peptides from N and C termini of RAD54L (ATRX)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot. ELISA. Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu ATRX

Target: ATRX (helicase 2, X-linked (ATRX))

Andere Bezeichnung: ATRX / XH2

Hintergrund: The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.Synonyms: RAD54L, Transcriptional regulator ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX

Gen-ID: 546

UniProt: P46100