Cyclin T1 Antikörper (AA 220-320)

Produktnummer ABIN3022810

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin T1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cyclin T1 Antikörper (AA 220-320) (ABIN3022810)

Target: Cyclin T1 (CCNT1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin T1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cyclin T1 Antikörper

Bindungsspezifität: AA 220-320

Sequenz: HWWEYVDATV TLELLDELTH EFLQILEKTP NRLKRIWNWR ACEAAKKTKA DDRGTDEKTS EQTILNMISQ SSSDTTIAGL MSMSTSTTSA VPSLPVSEES S

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 220-320 of human Cyclin T1 (NP_001231.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cyclin T1

Target: Cyclin T1 (CCNT1)

Andere Bezeichnung: CCNT1

Hintergrund: This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.,CCNT1,CCNT,CYCT1,HIVE1,cyclin-T1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,Immunology & Inflammation,CCNT1

Molekulargewicht: 21 kDa/80 kDa

Gen-ID: 904

UniProt: O60563