RUNX1 Antikörper (AA 150-250)

Produktnummer ABIN3022804

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch RUNX1 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RUNX1 Antikörper (AA 150-250) (ABIN3022804)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RUNX1 Antikörper

Bindungsspezifität: AA 150-250

Sequenz: AMKNQVARFN DLRFVGRSGR GKSFTLTITV FTNPPQVATY HRAIKITVDG PREPRRHRQK LDDQTKPGSL SFSERLSELE QLRRTAMRVS PHHPAPTPNP R

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human RUNX1 (NP_001745.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Andere Bezeichnung: RUNX1

Hintergrund: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.,RUNX1,AML1,AML1-EVI-1,AMLCR1,CBF2alpha,CBFA2,EVI-1,PEBP2aB,PEBP2alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Neuroscience,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,RUNX1

Molekulargewicht: 20-28 kDa/37 kDa/48-51 kDa

Gen-ID: 861

UniProt: Q01196