Claudin 7 Antikörper (AA 29-211)

Produktnummer ABIN3022751

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Claudin 7 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Claudin 7 Antikörper (AA 29-211) (ABIN3022751)

Target: Claudin 7 (CLDN7)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Claudin 7 Antikörper

Bindungsspezifität: AA 29-211

Sequenz: QWQMSSYAGD NIITAQAMYK GLWMDCVTQS TGMMSCKMYD SVLALSAALQ ATRALMVVSL VLGFLAMFVA TMGMKCTRCG GDDKVKKARI AMGGGIIFIV AGLAALVACS WYGHQIVTDF YNPLIPTNIK YEFGPAIFIG WAGSALVILG GALLSCSCPG NESKAGYRVP RSYPKSNSSK EYV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7 (NP_001298.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: CLDN7

Hintergrund: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.,CLDN7,CEPTRL2,CLDN-7,CPETRL2,Hs.84359,claudin-1,claudin-7,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN7

Molekulargewicht: 16 kDa/22 kDa

Gen-ID: 1366

UniProt: O95471

Pathways: Hepatitis C