RAD9A Antikörper (AA 162-391)

Produktnummer ABIN3022652

Der Kaninchen Polyklonal Anti-RAD9A-Antikörper wurde für WB und IHC validiert. Er ist geeignet, RAD9A in Proben von Human zu detektieren.

Kurzübersicht für RAD9A Antikörper (AA 162-391) (ABIN3022652)

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD9A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RAD9A Antikörper

Bindungsspezifität: AA 162-391

Sequenz: ALAEVTLGIG RGRRVILRSY HEEEADSTAK AMVTEMCLGE EDFQQLQAQE GVAITFCLKE FRGLLSFAES ANLNLSIHFD APGRPAIFTI KDSLLDGHFV LATLSDTDSH SQDLGSPERH QPVPQLQAHS TPHPDDFAND DIDSYMIAME TTIGNEGSRV LPSISLSPGP QPPKSPGPHS EEEDEAEPST VPGTPPPKKF RSLFFGSILA PVRSPQGPSP VLAEDSEGEG

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 162-391 of human RAD9A (NP_004575.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RAD9A

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Andere Bezeichnung: RAD9A

Hintergrund: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RAD9A,RAD9,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,RAD9A

Molekulargewicht: 42 kDa

Gen-ID: 5883

UniProt: Q99638

Pathways: Positive Regulation of Response to DNA Damage Stimulus