IL23R Antikörper (AA 405-629)
Kurzübersicht für IL23R Antikörper (AA 405-629) (ABIN3022246)
Target
Alle IL23R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 405-629
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Sequenz
- NSNVVKMLQE NSELMNNNSS EQVLYVDPMI TEIKEIFIPE HKPTDYKKEN TGPLETRDYP QNSLFDNTTV VYIPDLNTGY KPQISNFLPE GSHLSNNNEI TSLTLKPPVD SLDSGNNPRL QKHPNFAFSV SSVNSLSNTI FLGELSLILN QGECSSPDIQ NSVEEETTML LENDSPSETI PEQTLLPDEF VSCLGIVNEE LPSINTYFPQ NILESHFNRI SLLEK
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 405-629 of human IL23R (NP_653302.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IL23R (Interleukin 23 Receptor (IL23R))
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Andere Bezeichnung
- IL23R
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Hintergrund
- The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.,IL23R,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL23R
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Molekulargewicht
- 20 kDa/25 kDa/30 kDa/40 kDa/42 kDa/71 kDa
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Gen-ID
- 149233
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UniProt
- Q5VWK5
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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