Coagulation Factor IX Antikörper (AA 29-192)

Produktnummer ABIN3022174

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Coagulation Factor IX in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Coagulation Factor IX Antikörper (AA 29-192) (ABIN3022174)

Target: Coagulation Factor IX (F9)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor IX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Coagulation Factor IX Antikörper

Bindungsspezifität: AA 29-192

Sequenz: TVFLDHENAN KILNRPKRYN SGKLEEFVQG NLERECMEEK CSFEEAREVF ENTERTTEFW KQYVDGDQCE SNPCLNGGSC KDDINSYECW CPFGFEGKNC ELDVTCNIKN GRCEQFCKNS ADNKVVCSCT EGYRLAENQK SCEPAVPFPC GRVSVSQTSK LTRA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-192 of human Factor IX / F9 (NP_000124.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Andere Bezeichnung: F9

Hintergrund: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.,F9,F9 p22,FIX,HEMB,P19,PTC,THPH8,F9p22,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,Coagulation,F9

Molekulargewicht: 47 kDa/51 kDa

Gen-ID: 2158

UniProt: P00740