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UCP3 Antikörper (AA 1-110)

This anti-UCP3 antibody (ABIN3022086) is a Rabbit Polyclonal antibody detecting UCP3 in WB. Suitable for Human.
Produktnummer ABIN3022086

Kurzübersicht für UCP3 Antikörper (AA 1-110) (ABIN3022086)

Target

Alle UCP3 Antikörper anzeigen
UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

Reaktivität

  • 38
  • 25
  • 16
  • 1
  • 1
Human

Wirt

  • 39
  • 1
  • 1
Kaninchen

Klonalität

  • 40
  • 1
Polyklonal

Konjugat

  • 23
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser UCP3 Antikörper ist unkonjugiert

Applikation

  • 20
  • 15
  • 8
  • 3
  • 2
  • 2
Western Blotting (WB)
  • Bindungsspezifität

    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-110

    Sequenz

    MVGLKPSDVP PTMAVKFLGA GTAACFADLV TFPLDTAKVR LQIQGENQAV QTARLVQYRG VLGTILTMVR TEGPCSPYNG LVAGLQRQMS FASIRIGLYD SVKQVYTPKG

    Kreuzreaktivität

    Human, Maus

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human UCP3 (NP_073714.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

    Andere Bezeichnung

    UCP3

    Hintergrund

    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.,UCP3,SLC25A9,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Cardiovascular,Hypoxia,Lipids,Fatty Acids,UCP3

    Molekulargewicht

    22 kDa/29 kDa/34 kDa

    Gen-ID

    7352

    UniProt

    P55916

    Pathways

    Proton Transport
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