PDIA3 Antikörper (AA 206-505)

Produktnummer ABIN3021400

Dieses Anti-PDIA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDIA3 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für PDIA3 Antikörper (AA 206-505) (ABIN3021400)

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PDIA3 Antikörper

Bindungsspezifität: AA 206-505

Sequenz: FRPSHLTNKF EDKTVAYTEQ KMTSGKIKKF IQENIFGICP HMTEDNKDLI QGKDLLIAYY DVDYEKNAKG SNYWRNRVMM VAKKFLDAGH KLNFAVASRK TFSHELSDFG LESTAGEIPV VAIRTAKGEK FVMQEEFSRD GKALERFLQD YFDGNLKRYL KSEPIPESND GPVKVVVAEN FDEIVNNENK DVLIEFYAPW CGHCKNLEPK YKELGEKLSK DPNIVIAKMD ATANDVPSPY EVRGFPTIYF SPANKKLNPK KYEGGRELSD FISYLQREAT NPPVIQEEKP KKKKKAQEDL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human ERp57 (NP_005304.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: PDIA3

Hintergrund: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.,PDIA3,ER60,ERp57,ERp60,ERp61,GRP57,GRP58,HEL-S-269,HEL-S-93n,HsT17083,P58,PI-PLC,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,PDIA3

Molekulargewicht: 56 kDa

Gen-ID: 2923

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis