PRMT1 Antikörper (AA 20-353)
Kurzübersicht für PRMT1 Antikörper (AA 20-353) (ABIN3021312)
Target
Alle PRMT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-353
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Sequenz
- SSEKPNAEDM TSKDYYFDSY AHFGIHEEML KDEVRTLTYR NSMFHNRHLF KDKVVLDVGS GTGILCMFAA KAGARKVIGI ECSSISDYAV KIVKANKLDH VVTIIKGKVE EVELPVEKVD IIISEWMGYC LFYESMLNTV LYARDKWLAP DGLIFPDRAT LYVTAIEDRQ YKDYKIHWWE NVYGFDMSCI KDVAIKEPLV DVVDPKQLVT NACLIKEVDI YTVKVEDLTF TSPFCLQVKR NDYVHALVAY FNIEFTRCHK RTGFSTSPES PYTHWKQTVF YMEDYLTVKT GEEIFGTIGM RPNAKNNRDL DFTIDLDFKG QLCELSCSTD YRMR
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-353 of human PRMT1 (NP_938074.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))
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Andere Bezeichnung
- PRMT1
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Hintergrund
- This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.,PRMT1,ANM1,HCP1,HRMT1L2,IR1B4,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,PRMT1
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Molekulargewicht
- 39 kDa/40 kDa/41 kDa
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Gen-ID
- 3276
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UniProt
- Q99873
Target
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