BMP7 Antikörper (AA 132-431)

Produktnummer ABIN3021109

Der Kaninchen Polyklonal Anti-BMP7-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, BMP7 in Proben von Human zu detektieren.

Kurzübersicht für BMP7 Antikörper (AA 132-431) (ABIN3021109)

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-BMP7 Antikörper

Bindungsspezifität: AA 132-431

Sequenz: MVMSFVNLVE HDKEFFHPRY HHREFRFDLS KIPEGEAVTA AEFRIYKDYI RERFDNETFR ISVYQVLQEH LGRESDLFLL DSRTLWASEE GWLVFDITAT SNHWVVNPRH NLGLQLSVET LDGQSINPKL AGLIGRHGPQ NKQPFMVAFF KATEVHFRSI RSTGSKQRSQ NRSKTPKNQE ALRMANVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQT LVHFINPETV PKPCCAPTQL NAISVLYFDD SSNVILKKYR NMVVRACGCH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human BMP7 (NP_001710.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BMP7

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Andere Bezeichnung: BMP7

Hintergrund: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.,BMP7,OP-1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Ligand,BMP7

Molekulargewicht: 49 kDa

Gen-ID: 655

UniProt: P18075

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance