kappa Light Chain Antikörper (PE)

Produktnummer ABIN302034

Zitiert in 3+ Publikationen. Der PE-konjugierte Maus Monoklonal anti-kappa Light Chain Antikörper (Klon A8B5) (ABIN302034) detektiert spezifisch kappa Light Chain in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für kappa Light Chain Antikörper (PE) (ABIN302034)

Target: kappa Light Chain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser kappa Light Chain Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: A8B5

Produktdetails anti-kappa Light Chain Antikörper (PE)

Verwendungszweck: Anti-Hu Ig Kappa Light Chain PE

Keine Kreuzreaktivität: Ziege, Meerschweinchen, Hamster, Kaninchen, Schaf

Kreuzreaktivität (Details): Human

Produktmerkmale: The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze,Protect from prolonged exposure to light

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Referenzen für anti-kappa Light Chain Antikörper (PE) (ABIN302034)

Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, (2008) (PubMed).

Diaz de Domingo, Lardo, Romero Artaza, Merelli, Carbia, Sánchez Avalos: "[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]." in: Medicina, Vol. 59, Issue 1, pp. 11-6, (1999) (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, (1999) (PubMed).

Details zu kappa Light Chain

Target: kappa Light Chain

Andere Bezeichnung: Ig Kappa Light Chain

Hintergrund: Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin kappa, Igk

Gen-ID: 35