Lipocalin 2 Antikörper (AA 1-100)

Produktnummer ABIN3017526

Der Kaninchen Polyklonal Anti-Lipocalin 2-Antikörper wurde für WB und IF validiert. Er ist geeignet, Lipocalin 2 in Proben von Human zu detektieren.

Kurzübersicht für Lipocalin 2 Antikörper (AA 1-100) (ABIN3017526)

Target: Lipocalin 2 (LCN2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lipocalin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Lipocalin 2 Antikörper

Bindungsspezifität: AA 1-100

Sequenz: MPLGLLWLGL ALLGALHAQA QDSTSDLIPA PPLSKVPLQQ NFQDNQFQGK WYVVGLAGNA ILREDKDPQK MYATIYELKE DKSYNVTSVL FRKKKCDYWI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Lipocalin-2/NGAL (NP_005555.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Lipocalin 2

Target: Lipocalin 2 (LCN2)

Andere Bezeichnung: LCN2

Hintergrund: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.,LCN2,24p3,MSFI,NGAL,p25,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cardiovascular,Lipids,Fatty Acids,LCN2

Molekulargewicht: 22 kDa

Gen-ID: 3934

UniProt: P80188

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis