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CKMT1B Antikörper (AA 1-85)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CKMT1B in WB, IP und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3017246

Kurzübersicht für CKMT1B Antikörper (AA 1-85) (ABIN3017246)

Target

Alle CKMT1B Antikörper anzeigen
CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Reaktivität

  • 30
  • 18
  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 25
  • 5
Kaninchen

Klonalität

  • 27
  • 3
Polyklonal

Konjugat

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CKMT1B Antikörper ist unkonjugiert

Applikation

  • 29
  • 13
  • 13
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-85

    Sequenz

    MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPVRAA SERRRLYPPS AEYPDLRKHN NCMASHLTPA VYARLCDKTT PTGWT

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human CKMT1B (NP_066270.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

    Andere Bezeichnung

    CKMT1B

    Hintergrund

    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.,CKMT1B,CKMT,CKMT1,UMTCK,Signal Transduction,Kinase,CKMT1B

    Molekulargewicht

    47 kDa/50 kDa

    Gen-ID

    1159

    UniProt

    P12532
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