GRPR Antikörper (AA 235-384)

Produktnummer ABIN3017022

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRPR in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GRPR Antikörper (AA 235-384) (ABIN3017022)

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRPR Antikörper

Bindungsspezifität: AA 235-384

Sequenz: KNLIQSAYNL PVEGNIHVKK QIESRKRLAK TVLVFVGLFA FCWLPNHVIY LYRSYHYSEV DTSMLHFVTS ICARLLAFTN SCVNPFALYL LSKSFRKQFN TQLLCCQPGL IIRSHSTGRS TTCMTSLKST NPSVATFSLI NGNICHERYV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 235-384 of human GRPR (NP_005305.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GRPR

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Andere Bezeichnung: GRPR

Hintergrund: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.,GRPR,BB2,BB2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRPR

Molekulargewicht: 43 kDa

Gen-ID: 2925

UniProt: P30550