Acetylcholinesterase Antikörper (AA 398-617)

Produktnummer ABIN3016743

Der Kaninchen Polyklonal Anti-Acetylcholinesterase-Antikörper wurde für WB und IF validiert. Er ist geeignet, Acetylcholinesterase in Proben von Human zu detektieren.

Kurzübersicht für Acetylcholinesterase Antikörper (AA 398-617) (ABIN3016743)

Target: Acetylcholinesterase (AChE)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetylcholinesterase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Acetylcholinesterase Antikörper

Bindungsspezifität: AA 398-617

Sequenz: VPQVSDLAAE AVVLHYTDWL HPEDPARLRE ALSDVVGDHN VVCPVAQLAG RLAAQGARVY AYVFEHRAST LSWPLWMGVP HGYEIEFIFG IPLDPSRNYT AEEKIFAQRL MRYWANFART GDPNEPRDPK APQWPPYTAG AQQYVSLDLR PLEVRRGLRA QACAFWNRFL PKLLSATASE APSTCPGFTH GEAAPRPGLP LPLLLLHQLL LLFLSHLRRL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 398-617 of human ACHE (NP_056646.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Andere Bezeichnung: ACHE

Hintergrund: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.,ACHE,ACEE,ARACHE,N-ACHE,YT,Neuroscience,ACHE

Molekulargewicht: 58 kDa/65 kDa/67 kDa

Gen-ID: 43

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development