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PGC Antikörper (AA 100-200)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PGC in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3016695

Kurzübersicht für PGC Antikörper (AA 100-200) (ABIN3016695)

Target

Alle PGC Antikörper anzeigen
PGC (Pepsinogen C (PGC))

Reaktivität

  • 83
  • 24
  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 74
  • 29
  • 2
Kaninchen

Klonalität

  • 78
  • 27
Polyklonal

Konjugat

  • 45
  • 15
  • 10
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PGC Antikörper ist unkonjugiert

Applikation

  • 61
  • 41
  • 29
  • 25
  • 17
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-200

    Sequenz

    PSVYCQSQAC TSHSRFNPSE SSTYSTNGQT FSLQYGSGSL TGFFGYDTLT VQSIQVPNQE FGLSENEPGT NFVYAQFDGI MGLAYPALSV DEATTAMQGM V

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Pepsinogen II (NP_001159896.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:100 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    PGC (Pepsinogen C (PGC))

    Andere Bezeichnung

    PGC

    Hintergrund

    This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.,PGC,PEPC,PGII,gastricsin,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PGC

    Molekulargewicht

    34 kDa/42 kDa

    Gen-ID

    5225

    UniProt

    P20142
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