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Crk Antikörper (AA 1-304)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Crk in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3015531

Kurzübersicht für Crk Antikörper (AA 1-304) (ABIN3015531)

Target

Alle Crk (CRK) Antikörper anzeigen
Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Reaktivität

  • 87
  • 23
  • 18
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 75
  • 12
Kaninchen

Klonalität

  • 73
  • 14
Polyklonal

Konjugat

  • 44
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Crk Antikörper ist unkonjugiert

Applikation

  • 64
  • 35
  • 27
  • 27
  • 17
  • 12
  • 9
  • 7
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 28
    • 15
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-304

    Sequenz

    MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR SRQGSGVILR QEEAEYVRAL FDFNGNDEED LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL IGGNQEGSHP QPLGGPEPGP YAQPSVNTPL PNLQNGPIYA RVIQKRVPNA YDKTALALEV GELVKVTKIN VSGQWEGECN GKRGHFPFTH VRLLDQQNPD EDFS

    Kreuzreaktivität

    Human, Maus

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human CRK/CRKII (NP_058431.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

    Andere Bezeichnung

    CRK

    Hintergrund

    This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.,CRK,CRKII,p38,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,CRK

    Molekulargewicht

    22 kDa/33 kDa

    Gen-ID

    1398

    UniProt

    P46108

    Pathways

    Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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