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CXCR4 Antikörper (PE)

Name: CXCR4 Antikörper (PE)
Brand: antibodies-online
SKU: ABIN2967166
Price: 418.97 EUR
Availability: InStock

CXCR4 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal 12G5 PE

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD184 (12G5) PE antibody (10 μL reagent / 100 μL of peripheral whole blood). (CXCR4 Antikörper (PE))

FACS

Flow cytometry multicolor surface staining of human peripheral whole blood stained using anti-human CD184 (12G5) PE antibody (10 μL reagent / 100 μL of peripheral whole blood) and anti-human CD3 (UCHT1) APC antibody (10 μL reagent / 100 μL of peripheral whole blood). (CXCR4 Antikörper (PE))

FACS

Separation of human CD184 positive CD3 negative lymphocytes (red-filled) from CD184 negative CD3 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD184 (12G5) PE antibody (10 μL reagent / 100 μL of peripheral whole blood). (CXCR4 Antikörper (PE))

FACS

3 Abbildungen

Produktnummer ABIN2967166

Datenblatt (PDF)

Target Alle CXCR4 Antikörper anzeigen

CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Reaktivität
145

86

63

21

10

10

9

6

4

4

3

3

3

2

2

1

1

1

1
Human, Non-Human Primate
Wirt
118

29

12

9

1
Maus
Passende Sekundärantikörper
Klonalität
126

43
Monoklonal
Konjugat
96

8

7

6

6

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Dieser CXCR4 Antikörper ist konjugiert mit PE
Applikation
110

58

51

36

26

26

25

25

20

10

9

6

5

4

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.

Kreuzreaktivität (Details)

Human, Non-Human Primates

Aufreinigung

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen

CP-MAC-infected Sup-T1 cells

Klon

12G5

Isotyp

IgG2a kappa

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Applikationshinweise

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Kommentare

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Target

CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung

CD184 / CXCR4 (CXCR4 Produkte)

Hintergrund

C-X-C motif chemokine receptor 4,CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.,CXCR4, LAP3, LCR1, HM89, fusin, SDF1R

Gen-ID

7852

UniProt

P61073

Pathways

Regulation of Cell Size, CXCR4-mediated Signaling Events