Abeta 1-40 Antikörper
Kurzübersicht für Abeta 1-40 Antikörper (ABIN2961827)
Target
Alle Abeta 1-40 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Reacts with human and mouse Aβx-40
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Aufreinigung
- Purified
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Immunogen
- Synthetic peptide corresponding to Abeta35-40.
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Isotyp
- IgG1
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any application -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS pH 7.4
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Handhabung
- Dilute in PBS or medium which is identical to that used in the assay system.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for at least one year at -20°C
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Haltbarkeit
- 12 months
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- Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))
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Andere Bezeichnung
- Amyloid beta 1-40
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Hintergrund
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Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. There is a strong correlation between Aβ40 positivity and mature plaques. In the AD cortex, diffuse plaques, representing the earliest stage of Aβ deposition, are positive for Aβ42, but negative for Aβ40.
Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 40 Beta-APP40 Gene name: APP, A4, AD1 -
Gen-ID
- 351
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UniProt
- P05067
Target
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