beta Amyloid 1-16 Antikörper

Produktnummer ABIN2961825

Produktdetails

Target: beta Amyloid 1-16

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Spezifität: Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to Abeta1-16.

Klon: Ab3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any applications

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4.

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C

Haltbarkeit: 12 months

Antigendetails

Target: beta Amyloid 1-16

Andere Bezeichnung: Amyloid beta 1-16

Hintergrund: Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).

Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1

Gen-ID: 351

UniProt: P05067