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beta Amyloid 1-16 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in WB, IF, IP, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN2961825

Kurzübersicht für beta Amyloid 1-16 Antikörper (ABIN2961825)

Target

beta Amyloid 1-16

Reaktivität

Human, Maus

Wirt

  • 2
Maus

Klonalität

  • 1
  • 1
Monoklonal

Konjugat

  • 2
Unkonjugiert

Applikation

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Klon

Ab3
  • Spezifität

    Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42

    Aufreinigung

    Purified

    Immunogen

    Synthetic peptide corresponding to Abeta1-16.

    Isotyp

    IgG1
  • Applikationshinweise

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    1 - 10 μg/mL for any applications

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS, pH 7.4.

    Handhabung

    Dilute in PBS or medium which is identical to that used in the assay system.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for at least one year at -20°C

    Haltbarkeit

    12 months
  • Target

    beta Amyloid 1-16

    Andere Bezeichnung

    Amyloid beta 1-16

    Hintergrund

    Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).

    Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1

    Gen-ID

    351

    UniProt

    P05067
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