Tumor Protein p73 Antikörper (AA 2-13)

Produktnummer ABIN290399

Der Maus Monoklonal Anti-Tumor Protein p73 Antikörper wurde für WB, IHC, IHC (p) und ChIP validiert. Er ist geeignet, Tumor Protein p73 in Proben von Human und Affe zu detektieren.

Kurzübersicht für Tumor Protein p73 Antikörper (AA 2-13) (ABIN290399)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tumor Protein p73 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP)

Klon: 38C674-2

Produktdetails anti-Tumor Protein p73 Antikörper

Bindungsspezifität: AA 2-13

Spezifität: A peptide corresponding to amino acid residues 2-13 LYVGDPARHLAT of human dNp73. Mouse and human sequences are more than 95 % identical at these amino acid residues. In mouse, alanine at position 8 is replaced by methionine.

Homologie: Percent identity by BLAST analysis: Human, Gibbon, Monkey (100%) Mouse (92%).

Aufreinigung: Protein G purified

Immunogen: This antibody was developed against a peptide corresponding to amino acid residues 2-13 LYVGDPARHLAT of human dNp73. Mouse and human sequences are more than 95 % identical at these amino acid residues. In mouse, alanine at position 8 is replaced by methionine. Percent identity by BLAST analysis: Human, Gibbon, Monkey (100%), Mouse (92%).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ChrIP, IHC, IHC-P (5 μg/mL), WB (1 - 3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % BSA, 0.05 % sodium azide. Sourced in TCS.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Andere Bezeichnung: TP73 / p73

Hintergrund: Name/Gene ID: TP73

Synonyms: TP73, p53-like transcription factor, p73, p53-related protein, Tumor protein p73

Gen-ID: 7161

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus