DRD3 Antikörper

Produktnummer ABIN289418

Der Kaninchen Polyklonal Anti-DRD3-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, DRD3 in Proben von Human zu detektieren.

Kurzübersicht für DRD3 Antikörper (ABIN289418)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DRD3 Antikörper

Kreuzreaktivität (Details): This human D3R peptide showed no significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). It is 94 % conserved in monkey, 72 % with mouse and 68 % with rat D3R receptors.

Aufreinigung: Affinity chromatography purified

Immunogen: Dopamine D3 receptor antibody was raised in rabbit using a 19 amino acid peptide of human D3 R as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-1 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Affinity purified IgG lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Andere Bezeichnung: Dopamine D3 Receptor

Hintergrund: Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of Calleja and nucleus accumbens.

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity