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CSF3R Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CSF3R in FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2869977

Kurzübersicht für CSF3R Antikörper (ABIN2869977)

Target

Alle CSF3R Antikörper anzeigen
CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Reaktivität

  • 83
  • 24
  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 66
  • 19
  • 1
  • 1
  • 1
  • 1
Maus

Klonalität

  • 68
  • 21
Monoklonal

Konjugat

  • 48
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CSF3R Antikörper ist unkonjugiert

Applikation

  • 68
  • 34
  • 21
  • 18
  • 12
  • 10
  • 9
  • 4
  • 4
  • 3
  • 1
  • 1
Flow Cytometry (FACS)

Klon

LMM741
  • Verwendungszweck

    Anti-Hu CD114 Purified

    Spezifität

    The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.

    Keine Kreuzreaktivität

    Maus

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified by protein-A affinity chromatography.

    Reinheit

    > 95 % (by SDS-PAGE)

    Immunogen

    CHO cells transfected with human CD114

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Target

    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

    Andere Bezeichnung

    CD114

    Hintergrund

    Colony stimulating factor 3 receptor,CD114 / G-CSFR (granulocyte colony-stimulating factor receptor, also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF, granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation, survival, and differentiation. It is expressed by granulocytes at all stages of their differentiation, as well as by monocytes, dendritic cells, and mature platelets. Among non-hematopoietic cells, it is expressed e.g. by endothelial cells, placenta, trophoblasts, and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation, for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.,GCSFR, CSF3R, SCN7

    Gen-ID

    1441

    UniProt

    Q99062
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