PGE2 Antikörper

Produktnummer ABIN2869135

Dieses Anti-PGE2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PGE2 in IA. Geeignet für Human.

Kurzübersicht für PGE2 Antikörper (ABIN2869135)

Target: PGE2 (Prostaglandin E2 (PGE2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PGE2 Antikörper ist unkonjugiert

Applikation: Immunoassay (IA)

Klon: 5A2

Produktdetails anti-PGE2 Antikörper

Immunogen: PGE2 covalently coupled to carrier protein

Anwendungsinformationen

Applikationshinweise: For Immunoassay Use

Kommentare:

Mouse Monoclonal to Prostaglandin E2 (PGE2) Extend primary antibody supplies Clone 5A2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 mM Sodium Phosphate, 150 mM Sodium Chloride, 0.09 % Na Azide, pH 7.2

Details zu PGE2

Target: PGE2 (Prostaglandin E2 (PGE2))

Andere Bezeichnung: Prostaglandin E2

Hintergrund: Eicosanoid signal transduction pathways are highly conserved and are involved in a number of physiological processes. Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which con- vert the acid into PGH2. This is further processed by cytosolic or microsomal prostaglandin synthases to become PGE2 or one of several other prostanoids. Prostacyclin is the major cyclooxygenase product in blood vessel walls and it is present in inflammatory fluids in similar concentrations to PGE2. Prostacyclin is a potent vasodilator and is more potent than PGE2 in producing hyperalgesia. PGE2 is produced by a wide variety of tissues and in several pathological conditions, including inflammation, arthritis, fever, tissue injury, endometriosis, and a variety of cancers. Other biological actions of PGE2 include vasodilation, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption, and has thermoregula- tory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.