Der Kaninchen Polyklonal anti-Proteasome 20S Antikörper (ABIN285927) detektiert spezifisch Proteasome 20S in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Kurzübersicht für Proteasome 20S Antikörper (ABIN285927)
Target
Proteasome 20S
Reaktivität
Human
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Unkonjugiert
Applikation
Western Blotting (WB)
Kreuzreaktivität
Human, Maus
Aufreinigung
Purified
Immunogen
Proteasome 20 S antibody was raised in rabbit using a Mixture of synthetic peptides corresponding to residues C R(207) V I L G N/D E L P K F Y D E(220) of human and mouse proteasome 20 LMP2 as the immunogen.
WB: 1 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Purified IgG supplied in PBS with 0.05 % NaN3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C.
Target
Proteasome 20S
Hintergrund
LMP2 is a catalytic subunit of the 20S proteasome and, upon interferon gamma-induction, replaces the delta subunit. LMP2 alters the specificity of the 20S proteasome and is critical for the production of MHC class I ligands, production of T-lymphocytes, and is suggested to increase the efficiency of antigen presentation of the immune response.