Proteasome 20S Antikörper

Produktnummer ABIN285927

Produktdetails

Target: Proteasome 20S

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified

Immunogen: Proteasome 20 S antibody was raised in rabbit using a Mixture of synthetic peptides corresponding to residues C R(207) V I L G N/D E L P K F Y D E(220) of human and mouse proteasome 20 LMP2 as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Purified IgG supplied in PBS with 0.05 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Antigendetails

Target: Proteasome 20S

Synonyme: PSC5 antikoerper, ZETA antikoerper, proteasome subunit alpha 5 antikoerper, proteasome (prosome, macropain) subunit, alpha type 5 antikoerper, PSMA5 antikoerper, Psma5 antikoerper

Hintergrund: LMP2 is a catalytic subunit of the 20S proteasome and, upon interferon gamma-induction, replaces the delta subunit. LMP2 alters the specificity of the 20S proteasome and is critical for the production of MHC class I ligands, production of T-lymphocytes, and is suggested to increase the efficiency of antigen presentation of the immune response.