PDGF antibody was raised in goat using purified human PDGF-AB as the immunogen.
Isotyp
IgG
Applikationshinweise
Optimal conditions should be determined byt he investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Affi-Gel Blue purified protein supplied in 0.1 M tris-glycine, pH 7.0.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C.
Target
PDGF
Hintergrund
Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.