Neuroketals Antikörper

Produktnummer ABIN285871

Dieser Ziege Polyklonal Antikörper detektiert spezifisch Neuroketals in IHC, ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Säugetier.

Kurzübersicht für Neuroketals Antikörper (ABIN285871)

Target: Neuroketals

Reaktivität: Säugetier

Wirt: Ziege

Klonalität: Polyklonal

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Produktdetails

Immunogen: Neuroketal antibody was raised in goat using neuroketal-Conjugate as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: >1:4,000, IHC-P: >1:200, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Neat serum, with 0.1 % NaN3 as a preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Antigendetails

Target: Neuroketals

Andere Bezeichnung: Neuroketal

Hintergrund: Neuroketals and neuroprostanes are a class of compounds that result from the oxidation of docosahexenoic acid (DHA), which is enriched in the brain and retina, especially the synaptic membranes and retina. DHA is a membrane polyunsaturated fatty acid that is especially vulnerable to free radical attack because hydrogen radicals easily remove its double bonds. The DHA is oxidized to isoprostane-like compounds called neuroprostanes, which can dehydrate to form highly reactive A4/J4 neuroprostanes . Neuroprostanes can also undergo rearrangement to form D- and E-ring neuroprostanes. These reactive neuroprostanes are called neuroketals because DHA is so concentrated in the nervous system.