Dieses Anti-GAP43-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GAP43 in WB, IHC, IP und ICC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Affe und Cat.
ICC: 1:100-1:400, IHC: 1:2,000, IP: 1-10 µL, WB: 1:500-1:2,000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Neat rabbit antiserum, with 0.02 % NaN3
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C.
Target
GAP43
(Growth Associated Protein 43 (GAP43))
Andere Bezeichnung
GAP43
Hintergrund
GAP-43, a common marker of differentiating neurons, is expressed at elevated levels by developing or regenerating neurons during axon growth. While GAP-43 is an integral membrane protein associated with the cytoplasmic surface of axonal growth cones (and synapses), it is absent from dendritic growth cones. In adult brain, GAP-43 is found in highconcentration in presynaptic areas where memory formation is thought to occur, such asfrontal cortex, limbic system and hippocampus.