DRD3 Antikörper

Produktnummer ABIN285754

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DRD3 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für DRD3 Antikörper (ABIN285754)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DRD3 Antikörper

Spezifität: This AB is 100 % conserved in Mouse and Rat, 91% in Golden hamster, 83% in Rabbit and Pig, and 75% in Human and Canine.

Kreuzreaktivität (Details): This rat D3R peptide sequence is 88 % conserved in mouse and 63 % with human/monkey D3R receptors (1-2). No significant sequence homology with other dopamine receptors (D1, D2, D4 or D5).

Immunogen: Dopamine D3 receptor antibody was raised in rabbit using a 19 amino acid peptide of human D3 R as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-1 µg/mL, IHC: 2-10 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in PBS at 1 mg/mL.

Konzentration: Lot specific

Buffer: Lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Andere Bezeichnung: Dopamine D3 Receptor

Hintergrund: Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of Calleja and nucleus accumbens.

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity