HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Antikörper
Kurzübersicht für HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Antikörper (ABIN2857073)
Target
Alle HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
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Rabbit Polyclonal antibody to TIP30 (HIV-1 Tat interactive protein 2, 30 kDa)
TIP30 antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Full length human TIP30 Recombinant protein.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: A431 , HeLa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
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Andere Bezeichnung
- HIV-1 Tat interactive protein 2
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Hintergrund
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Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
Cellular Localization: Cytoplasm , Nucleus envelope -
Molekulargewicht
- 27 kDa
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Gen-ID
- 10553
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UniProt
- Q9BUP3
Target
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