CXCR4 Antikörper (Extracellular Domain, N-Term)
Kurzübersicht für CXCR4 Antikörper (Extracellular Domain, N-Term) (ABIN285681)
Target
Alle CXCR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Extracellular Domain, N-Term
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Kreuzreaktivität
- Xenopus laevis
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Immunogen
- CXCR4 antibody was raised in goat using YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor. as the immunogen.
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Applikationshinweise
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ELISA: 1:25,000, IHC: 1:150, WB: 1:500
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- 10 mM KHPO4, 140 M NaCl with 1 mg/mL BSA and 0.1 % NaN3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Andere Bezeichnung
- CXCR4
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Hintergrund
- Chemokine receptors are G protein-coupled receptors (GPCRs) and play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes.
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Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
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