Der Ziege Polyklonal anti-CXCR4 Antikörper (ABIN285681) detektiert spezifisch CXCR4 in WB, ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
CXCR4 antibody was raised in goat using YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor. as the immunogen.
Chemokine receptors are G protein-coupled receptors (GPCRs) and play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes.