SART1 Antikörper (C-Term)

Produktnummer ABIN2856790

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SART1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SART1 Antikörper (C-Term) (ABIN2856790)

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SART1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SART1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Xenopus laevis, Zebrafisch (Danio rerio), Rind (Kuh)

Kreuzreaktivität (Details): Mouse (99 %), Rat (99 %), Xenopus laevis (89 %), Zebrafish (81 %), Bovine (99 %)

Produktmerkmale: Rabbit polyclonal antibody to SART1 (squamous cell carcinoma antigen recognized by T cells)
SART1 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human SART1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*

Kommentare:

Positive Control: H1299 , HeLa , HepG2 , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SART1

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Andere Bezeichnung: SART1

Hintergrund: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Cellular Localization: Nucleus

Molekulargewicht: 90 kDa

Gen-ID: 9092

Pathways: Ribonucleoprotein Complex Subunit Organization