Fatty Acid Synthase Antikörper (N-Term)

Produktnummer ABIN2856754

Produktdetails anti-Fatty Acid Synthase Antikörper

Target: Fatty Acid Synthase (FASN)

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Fatty Acid Synthase (fatty acid synthase)
Fatty Acid Synthase antibody [N1N2], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4 , 293T , A431 , HeLa , HepG2

Validation: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: fatty acid synthase (FASN Produkte)

Synonyme: FAS antikoerper, OA-519 antikoerper, SDR27X1 antikoerper, FASN antikoerper, fj34h12 antikoerper, wu:fj34h12 antikoerper, Cgl0836 antikoerper, A630082H08Rik antikoerper, BcDNA:GH07626 antikoerper, BcDNA:gh07626 antikoerper, DM_7295848 antikoerper, Dmel\\CG3523 antikoerper, Fatty acid synthase antikoerper, anon-EST:Posey235 antikoerper, anon-EST:Posey43 antikoerper, anon-WO0138581.1 antikoerper, dFAS antikoerper, fas antikoerper, fatty acid synthase antikoerper, fatty acid synthase Fas antikoerper, type I polyketide synthase antikoerper, Fatty acid synthase Fas antikoerper, Fatty Acid SyNthase antikoerper, fatty-acid synthase antikoerper, fatty-acid synthase II antikoerper, fatty-acid synthase fas antikoerper, Fatty acid synthase 1 antikoerper, FASN antikoerper, fas antikoerper, Fasn antikoerper, BAD_RS01360 antikoerper, fasn antikoerper, fasn-1 antikoerper, NCgl0802 antikoerper, fasB antikoerper, MT2600 antikoerper, TBMG_01448 antikoerper, FASN1 antikoerper

Hintergrund: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Cellular Localization: Cytoplasm , Melanosome

Molekulargewicht: 273 kDa

Gen-ID: 2194

UniProt: P49327

Pathways: AMPK Signaling