CCR7 Antikörper (AA 2-22)

Produktnummer ABIN285675

Produktdetails anti-CCR7 Antikörper

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Bindungsspezifität: AA 2-22

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CCR7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunochromatography (IC)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7

Immunogen: CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: 10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.

Details zu CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Andere Bezeichnung: CCR7 (CCR7 Produkte)

Synonyme: zgc:165629 antikoerper, ccr7-a antikoerper, CD197 antikoerper, Cdw197 antikoerper, Cmkbr7 antikoerper, EBI1 antikoerper, Ebi1h antikoerper, BLR2 antikoerper, CDw197 antikoerper, CMKBR7 antikoerper, chemokine (C-C motif) receptor 7 antikoerper, C-C motif chemokine receptor 7 antikoerper, C-C motif chemokine receptor 7 L homeolog antikoerper, ccr7 antikoerper, CCR7 antikoerper, ccr7.L antikoerper, Ccr7 antikoerper

Hintergrund: C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process