CCR7 Antikörper (AA 2-22)
Kurzübersicht für CCR7 Antikörper (AA 2-22) (ABIN285675)
Target
Alle CCR7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 2-22
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                                            Kreuzreaktivität
- Human
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                                            Kreuzreaktivität (Details)
- Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7
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                                            Immunogen
- CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.
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                                            Isotyp
- IgG1
 
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                                            Applikationshinweise
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                        ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000
 Optimal conditions should be determined by the investigator.
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Konzentration
- Lot specific
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                                            Buffer
- 10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            Handhabung
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                        Avoid repeated freeze/thaw cycles. 
 Dilute only prior to immediate use.
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                                            Lagerung
- -20 °C/-80 °C
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                                            Informationen zur Lagerung
- Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.
 
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    - CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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                                            Andere Bezeichnung
- CCR7
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                                            Hintergrund
- C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.
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                                            Pathways
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
 Target
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