CCR7 Antikörper (AA 2-22)
Kurzübersicht für CCR7 Antikörper (AA 2-22) (ABIN285675)
Target
Alle CCR7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2-22
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Kreuzreaktivität
- Human
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Kreuzreaktivität (Details)
- Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7
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Immunogen
- CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- 10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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Andere Bezeichnung
- CCR7
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Hintergrund
- C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.
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Pathways
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
Target
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